Grant✓ Small businesses may apply
NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)
National Institutes of Health
- Opportunity #
- PAR-27-064
- Agency
- National Institutes of Health
- ALN (CFDA)
- 93.855
- Status
- posted
- Posted
- Jun 16, 2026
- Closes
- Jul 5, 2029
- Funding instrument
- Cooperative Agreement
- Category
- Health
- Cost sharing required
- No
Who can apply
- •Native American tribal organizations (other than Federally recognized tribal governments)
- •Private institutions of higher education
- •Independent school districts
- •Public and State controlled institutions of higher education
- •County governments
- •Small businesses
- •State governments
- •Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- •Special district governments
- •Native American tribal governments (Federally recognized)
- •For profit organizations other than small businesses
- •Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- •Public housing authorities/Indian housing authorities
- •City or township governments
- •Others (see text field entitled "Additional Information on Eligibility" for clarification)
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Synopsis
This notice of funding opportunity (NOFO) encourages applications for implementation of investigator-initiated, milestone driven clinical trials that need enhanced oversight, and as applicable, include mechanistic studies. Mechanistic work in clinical trials may be of great value because it promotes the understanding of human diseases and the development of future therapeutic modalities. Support is available for clinical trials up to 5 years, as well as for extended clinical trials of 6- or 7-years.Investigators are encouraged to visit this NIH website for additional information about the overall mission and research areas of NIAID.Only one clinical trial may be proposed in each NIAID Clinical Trial Implementation Cooperative Agreement (U01) application. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered.
Contact
National Institutes of Health · NIAID_IICT_U01@mail.nih.gov