Grant✓ Small businesses may apply
GREGoRi Innovation Projects (U01 Clinical Trial Optional)
National Institutes of Health
Award ceiling
$500,000
Award floor
$3
Program funding
$7,500,000
- Opportunity #
- RFA-HG-27-013
- Agency
- National Institutes of Health
- ALN (CFDA)
- 93.172
- Status
- posted
- Posted
- Jun 18, 2026
- Closes
- Oct 30, 2026
- Funding instrument
- Cooperative Agreement
- Category
- Health
- Cost sharing required
- No
Who can apply
- •State governments
- •Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- •County governments
- •For profit organizations other than small businesses
- •Others (see text field entitled "Additional Information on Eligibility" for clarification)
- •Independent school districts
- •Public housing authorities/Indian housing authorities
- •Native American tribal governments (Federally recognized)
- •Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- •Small businesses
- •Public and State controlled institutions of higher education
- •City or township governments
- •Special district governments
- •Native American tribal organizations (other than Federally recognized tribal governments)
- •Private institutions of higher education
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Synopsis
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.
Contact
National Institutes of Health · nhgri-gregor@mail.nih.gov